Optimasi Zeolit Alam Lampung (ZAL) Sebagai Penstabil Sediaan Antibakteri Esktrak Buah Mengkudu (Morinda citrifolia L.)
DOI:
https://doi.org/10.37090/jfl.v7i2.54Abstract
Noni fruit extract has been widely known as an antibacterial, but plant extracts are easily degraded by light, pH and temperature, thus reducing the antibacterial activity, zeolite is added to maintain the stability of the noni extract. This study uses an experimental method that is by comparing the inhibition zones that occur between noni fruit extract and noni + ZAL fruit extract and to test the stability of the preparation, the sample is heated at 40oC and then tested for antibacterial activity again. The statistical test results show the value of Asymp. Sig (0.003)References
Asriani. 2008. Profil Lampung Mencakup Data Penduduk Sumber Daya Alam dan Ekonomi Makro. http//:www.M.News.viva.co.idnews/read/3507provinsi_Lampung, [18 September 2014].
Nasikin, M. 1998. Sintesis Etilen dari
Etanol dengan Katalis H-Zeolit Alam. Jurnal Teknologi. XII, 296.
Damayanti, S.I., Ginting, S.B., Nur
Khasanah, Devi, O.V., Aufa, Y.S. 2015. Pengaruh aktivasi zeolit alam Lampung terhadap adsorben gas CO2 dari Biogas. Seminar Nasional Sains dan Teknologi VI, LPP UNILA.
Slamet, Ellyana M, Bismo, S. 2008. Modifikasi Zeolit Alam Lampung Dengan
Fotokalis TiO2 melalui Metode Sol Gel dan Aplikasinya Untuk Penyisihan Fenol. Jurnal Teknologi Universitas Indonesia.
Ginting A.B., Anggraini D, Indaryati S, Kriswarini R. 2007. Karakterisasi
Komposisi Kimia, Luas Permukaan Pori dan Sifat Termal dari Zeolit Bayah, Tasikmalaya, dan Lampung. J.Tek.Bhn.Nukl. 3(1):1-48.
Amalia, Fitri. 2012. Formulasi Ekstrak Kulit Buah Delima dan Daun Dewandaru Sebagai Sediaan Antibakteri dan Penggunaan Zeolit Untuk Menjaga Stabilitas Formula. Tesis. Institut Pertanian Bogor.
Choi G.J. 2009. In vitro and In vivo Antibacterial Activity of Punica granatum Peel Ethanol Extract Against Salmonella. eCAM oxfordjournals. Nep 105:1-8.
Peter, J.K. 2014. Antibacterial activity and of seed and leaf extract of Carica (papayavar pusa drawf L.) Journal of Pharmacy and Biological Science. Vol. 9 ; 20-37.
Sahoo, K., Dhal, N.K., Sahoo, S.L., Lenka, S.S. 2012. Comparative Phytochemical and Antimicrobial Study of Morinda Pubescens SM and Morinda citrifolia L. International Journal of Pharmacy and Pharmaceutical Sciences. Vol.4 (3) : 426-429.
Malinggas, F., Pangemanan, D.H.C.,Mariati, N.W. 2015. Uji Daya Hambat Ekstrak Buah Mengkudu Terhadap Pertumbuhan Streptococcus mutans Secara In Vitro. Jurnal Ilmiah Farmasi-UNSRAT. Vol. 4 (4) ; 22-26.
Puttarak P, Charoonratana T,
Panichayupakaranant. 2010. Antimicrobial Activity and Stability of Rhinacanthins-rich Rhinacanthus nasutus Exrtact. Phytomedicine Journal Elsevier. 17:323-327.
Franje C.A. 2010. Differential Heat Stability of Amphenicols Characterirized by Structural Degradation, Mass Spectrometry and Antimicrobial Activity. Journal of Pharmaceutical and Biomedical Analysis 53:869-877.
Sacramento, C.K., Ferreira, L.M., De Franca, L.P. 2014. Evaluation of Antitumoral and antimicrobial activity of Morinda citrifolia L. Grown in Southeast Brazil. Acta Cirurgia Brasileira. Vol. 29(2) : 10-14.
Murdiatt, T.B., Adiwinatai, G., Hildasari, D. 2000. Penelusuran Senyawa Aktif dari Buah Mengkudu (Morinda citrifolia L) Dengan Aktivitas Antelmintik Terhadap Haemonchus contortus. Jurnal Ilmu Ternak dan Veteriner. Vol. 5 (4) : 255-259.
Cooper GM., Hausman RE. 2007. The Cell : A Molecular Approach . 4th ed. Sunderland : Sinauer Associates, Inc.
Irnawati, D., Agustiono, P.,
Wardhani, E.H. 2010. Pengaruh Konsentarsi Cu dalam Cu-Zeolite Terhadap Daya Antibakteri Pada Streptococcus Mutans. Jurnal Zeolit Indonesia. Vol. 9 (2) : 47-53.
Sunarintyas, S., Harsini, Widyastuti, N.H., Inan, C.W. 2006. Pengaruh Aktivasi Panas dan Penambahan Cu Pada Zeolit Terhadap Daya Antimikroba Pada Staphylococcus aureus. IJD, edisi khusus KPPIG XIV.
