ANALISIS KEJADIAN STROKE BERULANG PADA PASIEN YANG MENGGUNAKAN ANTIPLATELET DI RUMAH SAKIT X CIAMIS

ANALYSIS OF RECURRENT STROKE INCIDENTS IN PATIENTS USING ANTIPLATELETTS AT X CIAMIS HOSPITAL

Authors

  • Seisa Wisastry Program Studi Farmasi, Universitas Bakti Tunas Husada, Tasikmalaya
  • Ilham Alifiar Program Studi Farmasi Universitas Bakti Tunas Husada, Tasikmalaya
  • Citra Dewi Salasanti Program Studi Farmasi, Universitas Bakti Tunas Husada, Tasikmalaya

DOI:

https://doi.org/10.37090/jfl.v13i2.1632

Abstract

Stroke is an acute and focal neurological deficit syndrome, which is clinically defined as the result of blood vessel injury in the central nervous system caused by rupture and blockage of blood vessels to the brain which results in reduced energy and the brain lacking nutrition. The aim of the study was to analyze the incidence of recurrent stroke in patients using antiplatelet drugs single aspirin, single clopidogrel and the combination at Hospital primary data obtained from the patient's medical record. Data and frequencies collected through patient medical records were analyzed using the chi-square test to determine the relationship between antiplatelet use and recurrent stroke. The results of this study showed that the number of stroke patients was 368 and recurrent stroke was 32 patients with an average duration of stroke recurrence, namely single aspirin 127.86 days, single clopidogrel 77 days, and the combination 237.39 days. From the data obtained, it can be concluded that Antiplatelet administration can affect the time to recurrent stroke.

Keywords:  Stroke, Antiplatelet, Aspirin, Clopidogrel, Combination

References

[1] Assaufi, M. H., Ardana, M., & Amir, M. (n.d.). Evaluasi Terapi Obat Antiplatelet Pada Pengobatan Pasien Stroke Di Instalasi Rawat Inap Rsud Am Parikesit Tenggarong Periode Tahun 2014. In Prosiding Seminar Nasional Kefarmasian Ke-4.

[2] Ayu, I. M., Epid, S. M., Prodi, D.,Masyarakat, K., Kesehatan, I.-I., & Pengantar, M. (n.d.). Pertemuan 11 Disain Studi Kohort.

[3] Megawati, S., Rahmawati, R., & Fhatonah, N. (2021). Evaluasi Penggunaan Obat Antiplatelet Pada Pasien Stroke Iskemik Di Instalasi Rawat Inap Rumah Sakit Umum Kabupaten Tangerang Tahun 2019. Jurnal Farmagazine, 8(1), 39. https://doi.org/10.47653/farm.v8i1.531.

[4] Octariani, S., Mayasari, D., & Ramadhan, A. M. (2021). Kajian Literatur: Perbandingan Efektivitas Antiplatelet Kombinasi Aspirin-Clopidogrel dan Aspirin pada Stroke Iskemik. Proceeding of Mulawarman Pharmaceuticals Conferences, 14, 405–412. https://doi.org/10.25026/mpc.v14i1.597

[5] Putra, I. D. G. R. C., Pinzon, R. T., Ardi, E., & Pramudita. (2022). The Correlation Between Compliance Medication of Antiplatelet Drugs Aspirin With Recurrent Ischemic Stroke At Bethesda Hospital in Yogyakarta. Media Farmasi, Vol. 13 No(1), 49–60.

[6] Raising, R., Hermawatiningsih, O. D., & Qibtiah, D. M. (2022). A comparison study between single aspirin antiplatelet and single clopidogrel antiplatelet on average period of recurrent stroke dr. Sayidiman Magetan. Media Farmasi: Jurnal Ilmu Farmasi, 19(1), 49. https://doi.org/10.12928/mf.v19i1.20639

[7] Tahir, R. W. M., Rija’i, H. R., & Indriyanti, N. (2021). Kajian Efektivitas Pengobatan pada Pasien Stroke Iskemik di Instalasi Rawat Inap RSUD Nunukan. Proceeding of Mulawarman Pharmaceuticals Conferences, 14, 254–261. https://doi.org/10.25026/mpc.v14i1.581

[8] Mutiarasari, D. (2019). Ischemic Stroke: Symptoms, Risk Factors, and Prevention. Medika Tadulako, Jurnal Ilmiah Kedokteran, 1(2), 36–44.

[10] Kementrian kesehatan RI. 2019. Yuk, Mengenal Apa itu Stroke. diunduh dari http://p2ptm.kemkes.go.id/infographic-p2ptm/stroke/yuk-mengenal-apa-itu-stroke pada tanggal 24 mei 2020.

[11] Dianita, Sari., Pagan, P., Nelly, A. 2013. Perbandingan Efektivitas Asetosal dan Kombinasi Asetosal-Klopidogrel terhadap Pasien Stroke Iskemik Akut. Berkala Kedokteran. Vol 9 (2): 109-118.

[12] Jessyca, F., Sasmita, P.K., 2021. Hubungan Tingkat Pendidikan dan Pengalaman Terkait Stroke Dengan Pengetahuan Stroke. Damianus Journal of Medicine, 20(1): 67-68.

[13] Laily, S.R., 2016. Hubungan Karakteristik Penderita dan Hipertensi Dengan Kejadian Stroke Iskemik. Jurnal Berkala Epidemiologi, 5(1): 56-57.

[14] Bonten, T. N., J. D. Snoep, W. J. J. Assendelft, J. J. Zwaginga, J. Eikenboom, M. V. Huisman, F. R. Rosendaal, dan J. G. Van Der Bom. 2015. Time-dependent effects of aspirin on blood pressure and morning platelet reactivity: a randomized cross-over trial. Hypertension. 65(4):743–750.

[15] Lukas, S. dan A. Pravita. 2020a. Perbandingan efektivitas penggunaan obat antiplatelet clopidogrel dan kombinasi clopidogrel dengan aspilet pada pasien stroke iskemik di rsud kab. bekasi. Social Clinical Pharmacy Indonesia Journal. 5(1):1–8.

Downloads

Published

2024-12-13

How to Cite

Wisastry, S., Ilham Alifiar, & Citra Dewi Salasanti. (2024). ANALISIS KEJADIAN STROKE BERULANG PADA PASIEN YANG MENGGUNAKAN ANTIPLATELET DI RUMAH SAKIT X CIAMIS: ANALYSIS OF RECURRENT STROKE INCIDENTS IN PATIENTS USING ANTIPLATELETTS AT X CIAMIS HOSPITAL. JFL : Jurnal Farmasi Lampung, 13(2). https://doi.org/10.37090/jfl.v13i2.1632

Most read articles by the same author(s)

Obs.: This plugin requires at least one statistics/report plugin to be enabled. If your statistics plugins provide more than one metric then please also select a main metric on the admin's site settings page and/or on the journal manager's settings pages.