Analisis Efektivitas Biaya (Cost Effectiveness Analysis) Penggunaan Antibiotik Seftriakson Dan Sefotaksim Pada Pasien Infeksi Saluran Kemih Di Rsd Dr. A. Dadi Tjokrodipo Bandar Lampung
DOI:
https://doi.org/10.37090/jfl.v12i2.1262Abstract
Cost-effectiveness analysis is defined as an analysis to identify, measure and compare significant costs and their consequences of alternative interventions. Antibiotics are a group of drugs most often used to treat infectious diseases. Ceftriaxone and cefotaxime are the main options for treating UTI. Urinary Tract Infection (UTI) is a disease with conditions where there are very large numbers of microorganisms in the urine and can cause infection in the urinary tract. This study was designed to analyze the cost-effectiveness of ceftriaxone and cefotaxime treatment for inpatient urinary tract infections at dr. A. Dadi Tjokrodipo. The method used is descriptive with a retrospective pharmacoeconomic analysis approach. The sampling technique was purposive sampling and sampling 92 patient. The research results show characteristics based on sex most are female as much as 55 (60%), based on age ≥56 years in 35 patients (38%), and the highest length of hospitalization was 3 days in 45 patients (49%). The most widely used profile of antibiotic drug use in patients with urinary tract infections was cefotaxime with a total of 64 patients (70%). The average cost for each type of drug therapy from ceftriaxone is 735,117 and sefotaxime is 742,178. Ceftriaxone has the highest percentage of therapeutic effectiveness at 86% compared to cefotaxime at 71%. Antibiotics that are more cost effective are ceftriaxone compared to cefotaxime with an ACER calculation of 78.455.
Keywords: Cost Effectiveness Analysis, Urinary Tract Infections, Ceftriaxone, Cefotaxime
References
Dipiro, J.t., Wells, B. G., Talbert, R. L. 2009. Pharmacoterapy Handbook, Seventh Edition. USA : Mc Graw-Hill Education
Wardhani, Kusumaning. 2019. Analisis Efektivitas Biaya Pengobatan Infeksi Saluran Kemih Menggunakan Antibiotik Seftriaxon dan Sefotaxim di RS Paru Ario Wirawan Salatiga. Journal of Holistics and Health Sciences Vol. 1
Rajabnia, M., Gooran S., Fazeli, 2012. Antibiotic Resistence Pattern in Urinary Tract Infection in Imam Ali Hospital Zahedan. 2010-2011. Zahedan Journal of Research in Medical Science.
Grabe M, Johanes, Cai. 2015. Guidelines on Urological Infection. European Association of Urology. Pranoto, E., Anis, K., dan Indri, H. 2012. Infeksi Saluran Kemih di Instalasi Rawat Inap RSUD Banyumas Periode Agustus 2009- Juli 2010. Pharmacy. Vol 09
Ghinorawa. 2015. Penatalaksanaan Infeksi Saluran Kemih dan Genitalia Pria 2015 2nd ed. Surabaya : Ikatan Ahli Urologi Indonesia
Lubis, M.A. dan Suprianto.2018. Analisis Cost-Effetiveness penggunaan Antidiabetes Oral pada Pasien Diabetes Melitus Tipe 2 Rawat Jalan Peserta BPJS di RSUP Haji Medan. Jurnal Dunia Farmasi 2(3): 128-147.
Ikatan Apoteker Indonesia. 2019. Informasi Spesialite Obat Indonesia.Volume 52 – Tahun 2019. Jakarta: Isfi Penerbitan
Anggi Restyana. 2019. Analisis Biaya Penggunaan Seftriakson dan Siprofloxacin Pasien Infeksi Saluran Kemih di Rumah Sakit X Kabupaten Jombang Tahun 2017. Institut Ilmu Kesehatan Bhakti Wiyata
KediriKusumawardani LA, Maria N, Fanani YN. Analisis potensi interaksi obat pada pasien rawat inap COVID- 19 pada suatu rumah sakit di Jawa Barat adanya reaksi efek samping yang tidak diinginkan. Pada bulan Juli 20. 2021;17(2).
Rachoin, J.S, et al. 2020. Impact of Length of Stay on Readmission in Hospitalized Patients. Cureus 12(9).
Rusli. 2016. Farmasi Rumah Sakit dan klinik. Jakarta: Pusdik SDM Kesehatan.
Rine, P. N.A.2020. Association Between Length of Stay and Readmission for COPD American Journal of Managed Care 23 : e253- e258
A. Rufaidah, Dkk. 2018. Analisis Efektivitas Dan Efek Samping Penggunaan Antibiotik Pada pasien Infeksi Saluran kemih Di Instalasi Rawat Inap RSUD Dr. Wahidin Sudirohusodo makasar. Universitas Hasanudin.
FF Baso. 2018. Efektivitas Antibiotic Golongan Sepalosporin Generasi Ke Dibandingkan Fluquinolon Terhadap Pasien ISK Di RS PKU Muhammadiyah Yogyakarta. Universitas Ahmad Dahlan.
Ikatan Apoteker Indonesia. 2019. Informasi Spesialite Obat Indonesia. Volume 52-Tahun 2019. Jakarta : Isfi penerbitan 18. Herawati N. Insulin Kerja-Panjang (long-Acting). Bio Trends. 2019;9(2):29-33. Murti, Tri. 2013. Farmakoekonomi Prinsip dan Metodologi. Yogyakarta : bursa ilmu