POTENSI INTERAKSI OBAT PADA PASIEN GASTRITIS DI PUSKESMAS RAWAT INAP WAY KANDIS BANDAR LAMPUNG TAHUN 2020
DOI:
https://doi.org/10.37090/jfl.v10i2.702Abstract
ABSTRACT
Gastritis is an inflammatory process in the mucous and sub-mucous layers of the stomach. The use of several drugs simultaneously facilitates the occurrence of drug interactions that are part of the Drug Related Problem (DRPs). This study aims to determine the potential for drug interactions in gastritis patients at the Puskesmas Rawat Inap Way Kandis Bandar Lampung in 2020. The research method carried out is observational research with a descriptive design taken retrospectively. The results of the study based on gender showed that there were 34 male patients (40.5%) and 50 female patients (59.5%). Then, based on the age group of 17-25 years, there were 26 patients (31%), aged 26-35 years as many as 16 patients (19%), aged 36-45 as many as 19 patients (22.6%), aged 46-55 as many as 13 patients (15.5%), aged 56-65 as many as 5 patients (6%), and aged >65 years as many as 5 patients (6%). The most use of gastritis drugs are antacids (92.8%), omeprazole (21.4%), ranitidine (15.1%). Drug interactions based on pharmacokinetic mechanisms were 20 cases (58.8%), and pharmacodynamic mechanisms were 14 cases (41.1%). Severity, 18 cases (52.9%) minor, 14 cases (41.1%) moderate, and 2 cases (5.8%) major. It was concluded that the potential drug interactions that experienced the incidence of drug interactions were 27 samples (32.1%) and 57 samples (67.8%) did not experience drug interactions.
 Keywords : Antacids, DRPs, Drug Interactions, Gastritis, Omeprazole, Ranitidine
References
Departemen Kesehatan Republik Indonesia. Undang-Undang Republik Indonesia Nomor 36 tentang Kesehatan. Jakarta : Kementerian Kesehatan Republik Indonesia. 2009
Kementerian Kesehatan Republik Indonesia. Peraturan Menteri Kesehatan Republik Indonesia Nomor 72 Tahun 2012 Tentang Sistem Kesehatan Nasional. Jakarta : Departemen Kesehatan Republik Indonesia. 2012
Kementerian Kesehatan Republik Indonesia. Peraturan Menteri Kesehatan Republik Indonesia Nomor 75 Tahun 2016, Tentang Pusat Kesehatan Masyarakat. Jakarta: Departemen Kesehatan Republik Indonesia. 2016
Kementerian Kesehatan Republik Indonesia. Peraturan Menteri Kesehatan Republik Indonesia Nomor 74 Tahun 2016, Tentang Standar Pelayanan Kefarmasian di Rumah Sakit. Jakarta: Departemen Kesehatan Republik Indonesia. 2016
Rijai Laode, Ghassani Karina Iffah, Widayat Wahyu. Profil Pengobatan dan DRP’S pada pasien Gangguan Lambung (Dyspepsia, Gastritis, Peptic Ulcer) di RSUD SAMARINDA. Samarinda. 2018.
Farikhah, H.N.,. Skripsi. Evaluasi Interaksi Obat Potensial pada Pasien Gastritis dan Dispepsia di Rawat Inap RSUD DR MOEWARDI tahun 2016. Fakultas Farmasi Muhamadiyah: Yogyakarta. 2017
Siyoto Pandu, Munith Abdul. Pengaruh Pola Makan Dan Merokok Terhadap Kejadian Gastritis Pada Lansia. Jurnal Keperawatan ISSN 1979–8091 Volume IX Nomor 3. 2016
Badan Pusat Statistik Provinsi Lampung. (2020). Jumlah kasus 10 penyakit terbanyak di provinsi lampung, 2017. Available from: https://lampung.bps.go.id/statictable/2020/05/22/524/jumlah-kasus-10-penyakit-terbanyak-di-provinsi-lampung-2017.html diakses pada 30 januari 2021
Wahyuni SS, Lestari Puji. Hubungan Polifarmsi dan Potensi Interaksi Obat Raniditin Pasien Rawat Inap di RSUD Ir. Soekarno Sukoharjo. Indonesian Journal On Medical Science Volume 8 No. 1, 2021
Sunaryo. Psikologi Untuk Keperawatan. EGC. Jakarta. 2006
Iwan Shalahudin, Udin Rosidin. “hubungan pola makan dengan gastritis pada remaja di sekolah menengah kejuruan YBKP3 garut†jurnal keseharan Bakti tunas husada 18: 33-44. 2018
Hartati, Sri, Jumaini, Wasisto Utomo. Hubungan Pola Makan Dengan Resiko Gastritis pada Mahasiswa yang menjalani KBK. JOM PSIK Vol.1 No.2. Program Studi Ilmu Keperawatan Universitas Riau : Riau. 2014
Amrulloh, F. M., Utami, N., Hubungan Konsumsi OAINS Terhadap Gastritis¸ Majority, Volume 2, Nomor 5, Fakultas Kedokteran Universitas Lampung. 2016
Ahmad A,. Peranan Omeprazole Injeksi Dalam Mengatasi Stress Ulcer, Bagian Ilmu Bedah, Fakultas Kedokeran Universitas Hasanudin Makassar. 2012
dr. Alvin Nursalm, SpPD. Diare Salah Satu Gejala Mag. 2022
Anonym. Basic Pharmacology & Drug Notes Edisi 2019. Makassar :MMN Publishing.
Drugs.com. Drug Interactions Checker [internet]. 2022. Available from : https://www.drugs,com/drug_interactions.html diakses pada 21 juli 2022
Adyana, A.W, Mintarsih, S.N., dan Rahmawati, A.Y. Hubungan antara Asupan Natrium, Kalium, Kalsium, dan Magnesium dengan Kejadian Hipertensi pada Remaja di SMA Negeri 10 Kota Semarang. Jurnal Riset Gizi. 4(1);2016 hal 1-8.
