PENGARUH PEMBERIAN EKSTRAK DAUN SAMBILOTO (ANDROGRAPHIS PANICULATA) TERHADAP TITER ANTIBODI AYAM RAS PETELUR
DOI:
https://doi.org/10.37090/jwputb.v7i1.710Abstract
This experiment aims to determine the effect of sambiloto (Andrographis paniculata) leaf extract on antibody titers of Avian Influenza (AI) and Newcastle Disease (ND) of starter phase laying hens. This study used 100 Isa Brown strain laying hens. The cages used were 20 box cages of 60x50x50 cm size. The research method used is a completely randomized design (CRD) with 5 treatments (T1: 0%, T2: 0,5%, T3: 1%, T4: 1,5% and T5: 2%) of sambiloto (Andrographis paniculata) leaf extract and each treatment was repeated 4 times. The result of the analysis of variance showed that the treatment of sambiloto (Andrographis paniculata) leaf extract had no significant effect (P>0,05) on AI and ND antibody titers at 3, 4 and 5 weeks of age, but has a significant effect (P<0,05) on AI and ND antibody titers at 6 weeks of age. In conclusion, the administrasion of sambiloto (Andrographis paniculata) leaf extract in drinking water was able to accelerate the formation AI and ND antibody titers and was able to maintain higher antibody compared to the control treatment. The administration of sambiloto (Andrographis paniculata) leaf extract in drinking water was able to form and maintain AI and ND antibody titers.
Keywords: antibody titers, avian influenza, laying hens, newcastke disease, sambiloto leaf extract
References
(OIE), O. I. des E. (2021). Avian Influenza (Infection with Avian Influenza Virus) Chapter 3.3.4. 3.3.4.
Aiyer-Harini, P., Ashok-Kumar, H. G., Kumar, G. P., & Shivakumar, N. (2013). An overview of immunologic adjuvants-A‎ review. J Vaccines Vaccin, 4(1), 1000167.
Alkandahri, M. Y., Subarnas, A., & Berbudi, A. (2018). Aktivitas Immunomodulator Tanaman Sambiloto (Andrographis paniculata Nees). Farmaka, 16(3), 16–20.
Astuti, P. (2016). Kajian Herbal Meniran (Phyllanthus niruri L) dan Sambiloto (Andrographis paniculata) sebagai Pengganti Feed Additive Komersial untuk Meningkatkan Tanggap Kebal dan Performans Ayam Buras. SNSE III 2016.
Kurnianto, A. B., Kencana, G. A. Y., & Astawa, I. N. M. (2016). Respons Antibodi Sekunder Terhadap Penyakit Tetelo pada Ayam Petelur Pascavaksinasi Ulangan Dengan Vaksin Tetelo Aktif. Jurnal Veteriner, 17(3), 331–336.
Levani, Y. (2018). Perkembangan Sel Limfosit B Dan Penandanya Untuk Flowcytometry. MAGNA MEDIKA: Berkala Ilmiah Kedokteran Dan Kesehatan, 1(5), 50–57.
Nugroho, A., Rahardiningtyas, E., Wicaksono Putro, D. B., & Wianto, R. (2016). Pengaruh Ekstrak Daun Sambiloto (Andrographis paniculata Ness.) terhadap Daya Bunuh Bakteri Leptospira sp. Media Penelitian Dan Pengembangan Kesehatan, 26(2), 77–84.
Sinaga, L., Suryanto, D., & Lesmana, I. (2016). Ekstrak Daun Sambiloto (Andrographis Paniculata) Dalam Mengendalikan Pertumbuhan Bakteri Aeromonas hydrophila, Edwardsiella tarda dan Jamur Saprolegnia sp. Secara In Vitro. AQUACOASTMARINE, 11(1), 106–119.
Sirat, M. M. P., Hartono, M., Santosa, P. E., Ermawati, R., Fauzi, T. A., Aini, N., Arzakiyah, F., Widodo, I., & Fauzan, T. A. (2022). PENGARUH SUPLEMENTASI EKSTRAK SAMBILOTO (Andrographis paniculata) MELALUI AIR MINUM TERHADAP TOTAL ERITROSIT DAN TOTAL LEUKOSIT BROILER. Jurnal Riset Dan Inovasi Peternakan, 6(1), 74–82.
Tizard, I. R. (2017). Veterinary Immunology-E-Book. Elsevier Health Sciences.
Widowati, M., Hardiyanti, C., Nisak, R., Sirat, M. M. P., & Ermawati, R. (2022). Suplementasi Tepung Daun Sambiloto (Andrographis paniculata) Melalui Air Minum Ayam Broiler Terhadap Titer Antibodi Newcastle Disease, Avian Influenza, dan Infectious Bursal Disease. Jurnal Ilmiah Peternakan Terpadu, 10(1), 114–123.
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