STUDI FARMAKOVIGILAN OBAT ANTIHIPERTENSI PADA PASIEN HIPERTENSI RAWAT JALAN DI DR. A. DADI TJOKRODIPO BANDAR LAMPUNG PERIODE OKTOBER–NOVEMBER 2021

Authors

  • Lilik Koernia Wahidah Program Studi Farmasi Universitas Tulang Bawang
  • Novita Tri Wahyuni Program Studi Farmasi Universitas Tulang Bawang
  • Dion Yongtama Program Studi Farmasi Universitas Tulang Bawang

DOI:

https://doi.org/10.37090/jfl.v11i2.814

Abstract

Hypertension, also known as high blood pressure, is systolic pressure140 and diastolic pressure 80 mmHg. The more blood pressure is pumped by the heart and the narrower the arteries, the higher the blood pressure. This study aims to determine the occurrence of adverse drug reactions in hypertensive patients in RSD DR. A. Dadi Tjokrodipo Bandar Lampung. This research is a descriptive research with total sampling method. Collecting data by looking at the patient's medical record data. The results showed that the female sex was more dominant in suffering from hypertension, namely 20 female patients (62.5%) and 12 male patients (37.5%). The highest age characteristics were found in the age range of 46-55 years as many as 14 patients (43.75%). The most characteristic of hypertension was in the case of stage 2 hypertension with a total of 17 patients (53.12%). The highest pattern of drug use was amlodipine (37.5%). The incidence of drug interactions was 10 cases (31.25%) with minor severity. The highest incidence of ADR was in the "moderately probable" 1-4 with a total of 15 cases (46.87%).

Keywords: ADR, hypertension, drug interactions, antihypertensive drugs

References

Japan International Coorpration Agency. 2020. Modul Farmakovigilans Dasar. Jakarta: Badan Pengawas Obat Dan Makanan.

Kumar, R, Ram, V.R., Prased, B.G., Mohanta, G.P., Manna, P.K. 2011. A Study Of Adverse Drug Reaction Due to Antyhypertensive Drugs in A Tertiary Care Teaching Hospital. International of Pharmacy & Life Sciences. (IJPLS), 2 (5).

Kementrian Kesehatan RI. 2013. Pedoman Teknis Penemuan dan Tatalaksana Hipertensi. Kementrian Kesehatan RI.

Pratiwi, P. P. 2018. Kajian Interaksi Obat Terhadap Pasien Geriatri Dengan Penyakit Hipertensi Di Rumah Sakit Pelabuhan Jakarta Utara. Jakarta: Fakultas Ilmu Kesehatan Program Studi Farmasi.

Nuraini, B. 2015. Risk Factors of Hypertension. J Majority. 4 (5).

Fadhila, S, N., Permana, D. 2020. The Use antihypertensive drugs in the treatments of essential hypertension at outpatient installations, Puskesmas Karang Rejo, Tarakan. Yarsi Journal of Pharmacology, 1(1).

Sa’idah, D. 2018. Evaluasi Rasionalitas Penggunaan Obat Antihipertensi di Instalasi Rawat Jalan RSUD Dr. Soegiri Lamongan Periode Tahun 2017. Malang: Fakultas Kedokteran Dan Ilmu Kesehatan Universitas Islam Negeri Maulana Malik Ibrahim.

Pusat Informasi Obat Nasional BPOM. 2015. Interaksi Obat. Diambil dari pionas.pom.go.id diakses 16 November 2021 pukul 13.16 WIB

Downloads

Published

2022-12-12

How to Cite

Koernia Wahidah, L. ., Tri Wahyuni, N. ., & Yongtama, D. . (2022). STUDI FARMAKOVIGILAN OBAT ANTIHIPERTENSI PADA PASIEN HIPERTENSI RAWAT JALAN DI DR. A. DADI TJOKRODIPO BANDAR LAMPUNG PERIODE OKTOBER–NOVEMBER 2021. JFL : Jurnal Farmasi Lampung, 11(2), 64–73. https://doi.org/10.37090/jfl.v11i2.814

Most read articles by the same author(s)

Obs.: This plugin requires at least one statistics/report plugin to be enabled. If your statistics plugins provide more than one metric then please also select a main metric on the admin's site settings page and/or on the journal manager's settings pages.