POTENSI INTERAKSI OBAT PADA PERESEPAN PASIEN  GERIATRI RAWAT JALAN DI PUSKESMAS SATELIT  BANDAR LAMPUNG TAHUN 2021

Hijrah Hijrah; Lilik  Koernia Wahidah; Ayu  Herawati; Adityo Adityo

doi:10.37090/jfl.v11i1.741

Penulis

Hijrah Hijrah Program Studi Farmasi Universitas Tulang Bawang
Lilik Koernia Wahidah Program Studi Farmasi Universitas Tulang Bawang
Ayu Herawati Program Studi Farmasi Universitas Tulang Bawang
Adityo Adityo Program Studi Farmasi Universitas Tulang Bawang

DOI:

https://doi.org/10.37090/jfl.v11i1.741

Abstrak

Drug interaction is the modification of the effect of a drug due to a drug being given alongside food, drinks or other drugs so that the effectiveness or toxicity of a drug changes. Some of the drugs prescribed in geriatric patients need to be considered so that no adverse drug interactions occur. This study aims to determine the potential for drug interactions in the prescribing of outpatient geriatric patients at the Bandar Lampung City Satellite Health Center in the 2021 period. This study is a non-experimental type with a descriptive design taken retrospectively. Sampling using purposive sampling method. The instruments in this study were medical records and prescriptions of geriatric patients, using the Drugs.com and Medscape applications. The results of this study showed that out of 256 prescriptions for geriatric patients there were 138 prescriptions (53.9%) who experienced drug interactions, with 120 male sex patients (46.9%) and female sex as many as 136 patients (53,1%). Based on the age category of 56-65 there were 110 patients (43%), aged 66-75 there were 120 patients (47%), and aged 76-90 there were 26 patients (10%). Drug interaction levels were minor category 51 patients (24.1%), moderate 140 patients (66.0%), and major 21 patients (9.9%). Based on the mechanism of pharmacodynamic interactions of 183 (86.3%) and pharmacokinetic interactions of 28 (13.7%). The conclusions of this study prove drugs administered to geriatric patients can cause drug interactions.

Keywords : Drug Interactions, Geriatric, Prescription

Referensi

Menteri Kesehatan RI. Peraturan menteri kesehatan republik indonesia nomor 75 Tahun 2014 tentang pusat kesehatan masyarakat. Jakarta; 2014.

Lea M, Rognan SE, Koristovic R, Wyller TB, Molden E. Severity and management of drug-drug interactions in acute geriatric patients. National Center Biotechnology Information. 2013;30(9):7–721.

Menteri Kesehatan RI. Penyelenggaraan pelayanan kesehatan lanjut usia di pusat kesehatan masyarakat. Jakarta; 2015.

Annisa N, Abdulah R. Potensi interaksi obat resep pasien geriatri: Studi retrospektif pada Apotek di Bandung. Jurnal Farmasi Klinis Indonesia. 2012;1(3):96–101.

Megawati, Hikmah N. Studi interaksi obat dan manifestasi klinik pada peresepan di puskesmas bontolempangan II kabupaten gowa. Studi Farmasi sandi karsa makasar. 2014;5-11.

Sejati EO, Lestari F, Mulqie L. Identifikasi interaksi obat pada pasien hipertensi di Puskesmas DTP Sindangbarang. Pros Farm. 2021;7(2):699–704.

Ja A. Drug interaction and pharmacist. Journal Young Pharmacy. 2012;2(3): 31-326.

Kholifah SN. Keperawatan Gerontik. 1st ed. 2016. hlm.1–112.

Afrilianto MB, Syamsi N, Asrinawati AN. Identifikasi interaksi obat pada pasien lanjut usia instalasi rawat jalan di rumah sakit umum daerah madani palu. Jurnal Kesehatan tadulako. 2020;6(1):28–31.

Utami PR, Handayani RP. Potensi interaksi obat pada pasien geriatri yang menggunakan antihipertensi di Puskesmas Karanggeneng Lamongan. Jurnal Surya. 2020;12(2):6–20.

Irawan AR, Wilar G. Evaluasi potensi interaksi obat pada resep pasien geriatri di instalasi farmasi rawat jalan di salah satu Rumah Sakit di Sukabumi. Farmaka. 2022;20(1):7–13.

drugs.com. Prescription drugs information, interactions and sides effects. 2021.